Table 1.

Upstream regulator analysis results of the differentially regulated genes obtained from the combination of microarray and RNA‐Seq data.

Upstream regulator	p‐value	Activation z‐score	Upstream regulator	p‐value	Activation z‐score
TGFB1	6.48E‐18	5.627	HDAC6	7.63E‐07	2.157
ERK	6.21E‐06	3.553	PGR	1.30E‐08	2.116
ERBB2	1.78E‐07	3.313	EGFR	1.71E‐04	2.109
SYVN1	2.29E‐07	3.298	IL5	9.10E‐02	2
P38 MAPK	3.25E‐07	3.146	RLIM	1.75E‐04	2
PDGF BB	1.41E‐12	3.112	SMARCD3	1.59E‐03	2
JNK	5.30E‐04	2.765	MAP3K14	1.87E‐02	2
GLI1	3.24E‐08	2.746	TAZ	5.14E‐05	2
PKC	2.87E‐04	2.574	NEDD9	6.69E‐03	2
HIF1A	4.18E‐10	2.552	RBPJ	2.00E‐03	−2
CCL5	3.11E‐03	2.449	MAP3K7	2.88E‐02	−2
RELA	1.11E‐02	2.425	miR‐29b‐3p	2.38E‐03	−2.219
PRKCD	1.35E‐03	2.414	HDAC	3.57E‐05	−2.273
CTGF	1.77E‐05	2.402	COL18A1	1.08E‐04	−2.538
TWIST1	3.13E‐04	2.236	WISP2	2.91E‐08	−2.714
EIF2AK2	4.87E‐02	2.236	FBN1	2.75E‐09	−2.797
MYB	1.20E‐04	2.215	FOXA1	1.08E‐04	−2.802
AKT	3.52E‐03	2.213	IgG	2.25E‐06	−3.5
TWIST2	1.26E‐04	2.207	MGEA5	1.30E‐13	−3.55
CSF2	1.62E‐01	2.2	SPDEF	6.24E‐14	−3.935
LDL	8.56E‐03	2.186	ER	1.38E‐15	−4.062

The top 30 predicted upstream regulators, sorted by p‐value, are reported in this table.