Table 2.
Baseline characteristics of patients with zoster and matched patients without zoster in Clinical Practice Research Datalink (n = 1 978 344) and by individual database
| With zoster | Without zoster | |
|---|---|---|
| Number of patients | 178 964 (100) | 1 799 380 (100) |
| Database | ||
| GOLD | 115 790 (64·7) | 1 169 272 (65·0) |
| Aurum | 63 174 (35·3) | 630 108 (35·0) |
| Sex female | 105 288 (58·8) | 1 050 183 (58·4) |
| Age at cohort entry (years), median (IQR) | 62·1 (48·2–74·1) | 61·5 (47·8–73·0) |
| Ethnicity | ||
| White | 120 898 (67·6) | 1 134 593 (63·1) |
| Not white | 6972 (3·9) | 88 200 (4·9) |
| Missing | 51 094 (28·5) | 576 587 (32·0) |
| Socioeconomic statusa | ||
| 1 (least deprived) | 46 031 (25·7) | 457 150 (25·4) |
| 2 | 42 099 (23·5) | 420 621 (23·4) |
| 3 | 36 479 (20·4) | 367 608 (20·4) |
| 4 | 30 979 (17·3) | 312 014 (17·3) |
| 5 (most deprived) | 23 376 (13·1) | 241 987 (13·4) |
| Body mass index category | ||
| Underweight | 3621 (2·0) | 35 887 (2·0) |
| Normal weight | 63 049 (35·2) | 615 593 (34·2) |
| Overweight | 59 671 (33·3) | 576 081 (32·0) |
| Obese | 38 539 (21·5) | 370 742 (20·6) |
| Missing | 14 084 (7·9) | 201 077 (11·2) |
| Smoking status | ||
| Never smoked | 64 372 (36·0) | 669 354 (37·2) |
| Currently smokes | 36 605 (20·5) | 394 526 (21·9) |
| Formerly smoked | 76 258 (42·6) | 685 093 (38·1) |
| Missing | 1729 (1·0) | 50 407 (2·8) |
| Comorbidity | ||
| Liver disease | 543 (0·3) | 5461 (0·3) |
| Asthma | 29 302 (16·4) | 237 518 (13·2) |
| Chronic kidney disease | 13 829 (7·7) | 108 374 (6·0) |
| Chronic obstructive pulmonary disease | 8747 (4·9) | 65 245 (3·6) |
| Depression | 5504 (3·1) | 49 097 (2·7) |
| Diabetes | 16 306 (9·1) | 146 446 (8·1) |
| Autoimmune disordersb | 4777 (2·7) | 34 800 (1·9) |
The data are presented as the number (%) unless otherwise stated. IQR, interquartile range. aMeasured by Index of Multiple Deprivation score: patient level, or practice level if patient level unavailable (GOLD, n = 1425). bRheumatoid arthritis, systemic lupus erythematosus or inflammatory bowel disease.