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. 2021 Nov 22;37:31. doi: 10.1186/s42826-021-00109-w

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Histopathological structures of the mid colon. A H&E stained sections of the mid colon from the Vehicle, LoMP, MiMP, and HiMP treated groups were observed at 200 × magnification using an optical microscope. B The histopathological parameters were determined using the Leica Application Suite. Four to six mice per group were used to prepare the H&E stained slides, and the histopathological parameters were measured in duplicate for each slide. The data are reported as the mean ± SD. *p < 0.05 compared with Vehicle treated group; #p < 0.05 compared with LoMP treated group; †p < 0.05 compared with MiMP treated group. Abbreviation: LoMP, Low concentration of microplastics; MiMP, Medium concentration of microplastics; HiMP, High concentration of microplastics