Fig. 4.

Verification of the differential expressions of prognostic ARGs. (A) The expression of APOL1 in GSE46517, and the expression of ATG16L2, DAPK2, ATG9B, and EGFR in GSE15605. N (T) = 31 and N (N) = 7 in GSE46517; N (T) = 46 and N (N) = 16 in GSE15605. *, P < 0.05; ***, P < 0.001. (B-F) The expression of APOL1 (B), ATG16L2 (C), DAPK2 (D), ATG9B (E) and EGFR (F) in three mutational signatures (BRAF, NF1 and RAS) and wild types (WT) of melanoma. The number of sorts: N (T) = 147 and N (N) = 558 in BRAF mutation; N (T) = 27 and N (N) = 558 in NF1 mutation; N (T) = 91and N (N) = 558 in RAS mutation; N (T) = 47and N (N) = 558 in WT. T = tumor, N = normal skin