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. 2021 Nov 22;12:585. doi: 10.1186/s13287-021-02653-7

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — MRI tracking of SPION labeled embryonic stem cells. A MRI images of the Sham-contra-hESC group showed a reduction of low signal intensity area in the striatum as time passes and detection of the area in another side of the brain. B MRI images of the HD-contra-hESC group showed expansion and migration (yellow arrow) of the low signal intensity area in the striatum as time passes and detection of hESCs in the other side of the brain. C MRI images of the Sham-ipsi-hESC group showed no changes of low signal intensity area in the striatum as time passes. D MRI images of the HD-ipsi-hESC group showed expansion and migration (yellow arrow) of low signal intensity area in the striatum as time passes