Table 1.
The baseline characteristics in this study
| Overall | MACEs | non-MACEs | ||
|---|---|---|---|---|
| n = 2293 | n = 186 | n = 2107 | p | |
| Clinical data | ||||
| Age (years) | 55.62 ± 11.01 | 57.73 ± 9.8 | 55.44 ± 11.09 | 0.006 |
| Male sex n(%) | 1387 (60.5) | 111 (59.7) | 1276 (60.6) | 0.813 |
| BMI (kg/m2) | 25.63 ± 3.38 | 25.95 ± 3.37 | 25.6 ± 3.38 | 0.175 |
| CAD n(%) | 1447 (63.1) | 142 (76.3) | 1305 (61.9) | < 0.001 |
| DM n(%) | 538 (23.5) | 60 (32.3) | 478 (22.7) | 0.003 |
| Hypertension n(%) | 1418 (61.8) | 125 (67.2) | 1293 (61.4) | 0.116 |
| Smoking n(%) | 788 (34.4) | 63 (33.9) | 725 (34.4) | 0.882 |
| Drinking n(%) | 468 (20.4) | 44 (23.7) | 424 (20.1) | 0.252 |
| Family history of CAD n(%) | 514 (22.4) | 30 (16.1) | 484 (23) | 0.032 |
| SBP (mmHg) | 128.05 ± 18.01 | 129.57 ± 16.49 | 127.92 ± 18.13 | 0.231 |
| DBP (mmHg) | 79.59 ± 11.19 | 80.25 ± 11.98 | 79.53 ± 11.12 | 0.398 |
| Laboratory parameters | ||||
| TC (mmol/L) | 4.9 ± 1.09 | 5.09 ± 1.08 | 4.88 ± 1.09 | 0.014 |
| TG (mmol/L) | (1.15,2.3) | 1.65 (1.17,2.36) | 1.58 (1.14,2.29) | 0.598 |
| HDL-C (mmol/L) | 1.11 ± 0.35 | 1.11 ± 0.34 | 1.16 ± 0.37 | 0.074 |
| LDL-C (mmol/L) | 3.2 ± 1.0 | 3.35 ± 1.01 | 3.18 ± 1.0 | 0.030 |
| Glu (mmol/L) | 5.65 ± 1.88 | 5.84 ± 2.44 | 5.63 ± 1.83 | 0.145 |
| HbA1C (%) | 6.02 ± 1.0 | 6.24 ± 1.06 | 6.0 ± 1.0 | 0.001 |
| hsCRP (mg/L) | 1.37 (0.72,2.46) | 1.65 (0.77,2.89) | 1.36 (0.72,2.46) | 0.192 |
| PCSK9 (ng/mL) | 228.48 (189,275.5) | 246.69 (208.92,297.11) | 227.24 (187.33,274.18) | < 0.001 |
| Coagulation indexes | ||||
| APTT (s) | 36.25 ± 3.9 | 36 ± 3.91 | 36.27 ± 3.89 | 0.374 |
| PT (s) | 12.75 ± 0.64 | 12.66 ± 0.58 | 12.76 ± 0.64 | 0.032 |
| PT-t (1/s) | 0.83 (0.63.1.25) | 0.91 (0.70,1.25) | 0.83 (0.63,1.25) | 0.028 |
| TT (s) | 16.4 ± 1.25 | 16.28 ± 1.55 | 16.41 ± 1.22 | 0.170 |
| Fib (g/L) | 3.06 ± 0.73 | 3.19 ± 0.85 | 3.05 ± 0.71 | 0.013 |
| D dimer (μg/mL) | 0.31 (0.24,0.41) | 0.31 (0.23,0.45) | 0.31 (0.24,0.41) | 0.531 |
| Platelet(10^12) | 216.79 ± 55.66 | 212.69 ± 49.81 | 217.15 ± 56.14 | 0.295 |
| Medication | ||||
| Aspirin/Clopidogrel n(%) | 748 (32.6) | 72 (38.7) | 676 (32.1) | 0.065 |
| ACEI/ARB n(%) | 383 (16.7) | 34 (18.3) | 349 (16.6) | 0.548 |
BMI body mass index, CAD coronary artery disease, DM diabetes mellitus, SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, TG triglyceride; HDL-C, high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, Glu glucose, HbA1C hemoglobin A1C, hs-CRP high-sensitivity C-reactive protein, PCSK9 proprotein convertase subtilisin/kexin type 9, APTT activated partial thromboplastin time, PT prothrombin time, PT-t transformation of prothrombin time (the inverse of the difference between PT and the minimal PT of normal plasma), TT thrombin time, Fib fibrinogen, ACEI angiotensin converting enzyme inhibitors, ARB angiotensin receptor blockers. p < 0.05 suggested significant difference