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. 2021 Nov 21;19:381. doi: 10.1186/s12951-021-01127-5

Scheme 1.

Scheme 1

Schematic overview of the composition and synergistic mechanisms for the co-delivery nanoparticles in the fibroblast-enriched microenvironment of gastric cancer (GC). a A scheme illustrating the preparation of PSN38@TPL-nsa nanoparticles, including self-assembling and drug loading. b Schematic illustration of PSN38@TPL-nsa for synergistic therapy against GC by inactivation cancer-associated fibroblasts (CAFs) and sensitized GC cells to SN38