Table 2.
Statin prescription based on ACC/AHA eligibility groups for primary prevention
| Variable | Eligible Patients | Statin Prescribed | High* Intensity Statin | Moderate† Intensity Statin | Women Prescribed Statin | Men Prescribed Statin | P value |
|---|---|---|---|---|---|---|---|
|
| |||||||
| LDL ≥190 mg/dL‡ | 194 | 112 (57.7%) | 65 (58.0%) | 44 (39.2%) | 92/152 (60.5%) | 20/42 (47.6%) | 0.14 |
| Diabetes mellitus† | 2751 | 2024 (73.6%) | 1070 (52.9%) | 871 (43.0%) | 1273/1778 (71.6%) | 751/973 (77.2%) | 0.001 |
| ASCVD risk ≥ 20%§ | 1270 | 769 (60.6%) | 359 (46.7%) | 360 (46.8%) | 440/720 (61.1%) | 329/550 (59.8%) | 0.64 |
| ASCVD risk ≥ 7.5% & < 20%§ | 2891 | 1006 (34.8%) | 383 (38.1%) | 565 (56.2%) | 688/1954 (35.2%) | 318/937 (33.9%) | 0.50 |
| Without RE∥ | 1899 | 600 (31.6%) | 226 (37.7%) | 335 (55.8%) | 393/1249 (31.5%) | 207/650 (31.8%) | |
| With RE∥ | 992 | 406 (40.9%) | 157 (38.7%) | 232 (57.1%) | 295/705 (41.8%) | 111/287 (38.7%) | |
| ASCVD risk ≥ 5% & < 7.5%‡ with RE∥ | 444 | 83 (18.7%) | 27 (32.5%) | 47 (56.6%) | 70/352 (19.9%) | 13/92 (14.1%) | 0.21 |
| Total | 7550 | 3994 | 1904 | 1887 | 2563 | 1431 | |
ACC = American College of Cardiology; AHA = American Heart Association; LDL = low-density lipoprotein; RE = risk enhancer; all other abbreviations as in Table 1.
High intensity statin: atorvastatin 40 to 80 mg, rosuvastatin 20 to 40 mg.
Moderate intensity statin: atorvastatin 10 to 20 mg, rosuvastatin 5 to 10 mg, simvastatin 20 to 40 mg, pravastatin 40 to 80 mg, lovastatin 40 mg, fluvastatin 80 or 40 mg BID, pitavastatin 3 to 4 mg.
Inclusion: age 20 to 75. Inclusion: age 40 to 75, LDL ≥70 and <190 mg/100 ml, no DM.
Inclusion: age 40 to 75, LDL< 190 mg/100 ml.
Risk enhancers included: family history of premature ASCVD, LDL ≥160, chronic kidney disease, inflammatory diseases, persistently elevated triglycerides ≥175, high sensitivity C-reactive protein ≥2.