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. Author manuscript; available in PMC: 2022 Dec 15.
Published in final edited form as: Am J Cardiol. 2021 Dec 15;161:36–41. doi: 10.1016/j.amjcard.2021.08.070

Table 2.

Statin prescription based on ACC/AHA eligibility groups for primary prevention

Variable Eligible Patients Statin Prescribed High* Intensity Statin Moderate Intensity Statin Women Prescribed Statin Men Prescribed Statin P value

LDL ≥190 mg/dL 194 112 (57.7%) 65 (58.0%) 44 (39.2%) 92/152 (60.5%) 20/42 (47.6%) 0.14
Diabetes mellitus 2751 2024 (73.6%) 1070 (52.9%) 871 (43.0%) 1273/1778 (71.6%) 751/973 (77.2%) 0.001
ASCVD risk ≥ 20%§ 1270 769 (60.6%) 359 (46.7%) 360 (46.8%) 440/720 (61.1%) 329/550 (59.8%) 0.64
ASCVD risk ≥ 7.5% & < 20%§ 2891 1006 (34.8%) 383 (38.1%) 565 (56.2%) 688/1954 (35.2%) 318/937 (33.9%) 0.50
Without RE 1899 600 (31.6%) 226 (37.7%) 335 (55.8%) 393/1249 (31.5%) 207/650 (31.8%)
With RE 992 406 (40.9%) 157 (38.7%) 232 (57.1%) 295/705 (41.8%) 111/287 (38.7%)
ASCVD risk ≥ 5% & < 7.5% with RE 444 83 (18.7%) 27 (32.5%) 47 (56.6%) 70/352 (19.9%) 13/92 (14.1%) 0.21
Total 7550 3994 1904 1887 2563 1431

ACC = American College of Cardiology; AHA = American Heart Association; LDL = low-density lipoprotein; RE = risk enhancer; all other abbreviations as in Table 1.

*

High intensity statin: atorvastatin 40 to 80 mg, rosuvastatin 20 to 40 mg.

Moderate intensity statin: atorvastatin 10 to 20 mg, rosuvastatin 5 to 10 mg, simvastatin 20 to 40 mg, pravastatin 40 to 80 mg, lovastatin 40 mg, fluvastatin 80 or 40 mg BID, pitavastatin 3 to 4 mg.

Inclusion: age 20 to 75. Inclusion: age 40 to 75, LDL ≥70 and <190 mg/100 ml, no DM.

§

Inclusion: age 40 to 75, LDL< 190 mg/100 ml.

Risk enhancers included: family history of premature ASCVD, LDL ≥160, chronic kidney disease, inflammatory diseases, persistently elevated triglycerides ≥175, high sensitivity C-reactive protein ≥2.