Table 3.
Patient Characteristics Associated with Statin Prescription for Primary Prevention.
| Variable | % Prescribed Statin | Unadjusted OR (95% CI) | Adjusted OR (95% CI)* | P value |
|---|---|---|---|---|
|
| ||||
| Age (years) | ||||
| <65 | 1822/4267 (42.7%) | 1 [Reference] | 1 [Reference] | NA |
| 65–75 | 2172/3283 (66.2%) | 2.62 (2.38 – 2.88) | 2.26 (2.01 – 2.53) | <0.001 |
|
| ||||
| Men | 1431/2594 (55.2%) | 1 [Reference] | 1 [Reference] | NA |
| Women | 2563/4956 (51.7%) | 0.87 (0.79 – 0.96) | 0.79 (0.71 – 0.88) | <0.001 |
|
| ||||
| White | 481/1004 (47.9%) | 1 [Reference] | 1 [Reference] | NA |
| Black | 442/957 (46.2%) | 0.93 (0.78 – 1.11) | 0.85 (0.69 – 1.04) | 0.10 |
| Asian | 111/198 (56.1%) | 1.39 (1.02 – 1.89) | 1.09 (0.71 – 1.53) | 0.62 |
| Other/unknown | 2918/5391 (54.1%) | 1.28 (1.12 – 1.47) | 1.10 (0.95 – 1.28) | 0.21 |
|
| ||||
| Not Hispanic | 1270/2634 (48.2%) | 1 [Reference] | 1 [Reference] | NA |
| Hispanic | 2724/4916 (55.4%) | 1.33 (1.21 – 1.47) | 1.25 (1.12 – 1.39) | <0.001 |
|
| ||||
| Hypertension | ||||
| No | 1710/3746 (45.6%) | 1 [Reference] | 1 [Reference] | NA |
| Yes | 2277/3778 (60.3%) | 1.81 (1.65 – 1.98) | 1.36 (1.23 – 1.51) | <0.001 |
| Smoker | ||||
| No | 2975/5723 (52.0%) | 1 [Reference] | 1 [Reference] | NA |
| Yes | 1019/1827 (55.8%) | 1.16 (1.05 – 1.30) | 1.19 (1.06 – 1.35) | 0.004 |
|
| ||||
| Risk Enhancers | ||||
| 0 | 2124/4225 (50.3%) | 1 [Reference] | 1 [Reference] | NA |
| 1+ | 1870/3325 (56.2%) | 1.27 (1.16 – 1.39) | 1.29 (1.12 – 1.49) | <0.001 |
|
| ||||
| Eligibility Criteria | ||||
| ASCVD 5% – 7.5% with RE | 83/444 (18.7%) | 1 [Reference] | 1 [Reference] | NA |
| ASCVD 7.5% – 20% without RE | 600/1899 (31.6%) | 2.01 (1.56 – 2.61) | 1.78 (1.34 – 2.39) | <0.001 |
| ASCVD 7.5% – 20% with RE | 406/992 (40.9%) | 3.01 (2.31 – 3.96) | 2.06 (1.57 – 2.73) | <0.001 |
| ASCVD ≥ 20% | 769/1270 (60.6%) | 6.66 (5.14 – 8.72) | 3.42 (2.56 – 4.61) | <0.001 |
| Diabetes mellitus | 2024/2751 (73.6%) | 12.1 (9.42 – 15.65) | 8.76 (6.74 – 11.52) | <0.001 |
| Low-density lipoprotein ≥ 190 mg/dL | 112/194 (57.7%) | 5.91 (4.10 – 8.62) | 4.44 (3.04 – 6.52) | <0.001 |
Abbreviations: CI = confidence interval; NA = not applicable; OR = odds ratio; all other abbreviations as in Table 1 and 2.
*
Adjusted odds ratios were obtained from a multivariable logistic regression with statin prescription as the outcome variable and the above baseline characteristics as independent variables.