Table 4.

Results of receiver operating characteristic (ROC) curve of fractional anisotropy (FA) of the selected grey matter regions with calculation of cut-off values, area under the curve (AUC), accuracy, sensitivity, and specificity in differentiating patients and controls

Variable		ROI site	Cut-off value	AUC	Sens.	Spec.	PPV	NPV	Accuracy
FA	RT	Thalamus	0.3	0.983	97%	93.3%	97%	93.3%	95.8%
		Globus pallidus	0.2	0.984	93.9%	73.3%	88.6%	84.6%	87.5%
		Hippocampal head	0.22	0.986	97%	73.3%	88%	91.7%	89.6%
	LT	Thalamus	0.26	0.691	72.7%	53.3%	77.1%	47.1%	66.7%
		Globus pallidus	0.17	0.433	45.5%	40%	62.5%	25%	43.8%
		Hippocampal head	0.17	0.895	84.8%	80%	90.3%	70.6%	83.3%