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Upstream regulators
| Upstream regulator | Predicted activation state | Activation z-score | P-value of overlap |
|---|---|---|---|
| TNF-α | Activated | 7.017 | 2E−21 |
| IL1-β | Activated | 6.412 | 7E−30 |
| IFN-γ | Activated | 6.013 | 8E−20 |
| IL−6 | Activated | 5.941 | 3E−23 |
| NFκβ (complex) | Activated | 5.921 | 4E−20 |
| IL1-α | Activated | 5.308 | 5E−22 |
| MYD88 | Activated | 4.957 | 8E−15 |
| CSF2 | Activated | 4.793 | 2E−17 |
| IL−2 | Activated | 4.631 | 8E−16 |
| TLR3 | Activated | 4.565 | 2E−12 |
