TABLE 1.

Patient Characteristics and Baseline Quantitative CT Parameters

	Mild (n = 12)	Moderate (n = 31)	Severe (n = 8)	P	Post Hoc Comparison
Sex (F/M) (n)	7/5	14/17	2/6	0.344
Age	45.7 ± 12	48.8 ± 16.8	55 ± 10	0.386
Symptom onset-baseline CT scan (d)	2.25 ± 2.4	3.16 ± 2.6	7.25 ± 4.3	0.016	Mild vs moderate, P = 1.00 Mild vs severe, P = 0.016 Moderate vs severe, P = 0.046
Length of hospital stay (d)	4.5 (7) [2–31]	9 (11) [3–42]	18 (13.75) [12–31]	0.004	Mild vs moderate, P = 0.560 Mild vs severe, P = 0.003 Moderate vs severe, P = 0.022
Patients with ICU admission (n,%)	1 (8.3%)	5 (16%)	6 (75%)	0.002
The number of affected lobes (n)	0	3 (4) [1–5]	5 (0)	0.001
Total lung volume (mL)	4332 ± 1463	4679 ± 1349	4163 ± 1065	0.543
Opacity score	0	3 (4) [1–9]	6 (1.75) [5–14]	˂0.001	Mild vs moderate, P ˂ 0.001 Mild vs severe, P ˂ 0.001, Moderate vs severe, P = 0.014
Opacity volume (mL)	0	8.3 (78) [0.11–564]	517.5 (642) [27–2731]	˂0.001	Mild vs moderate, P ˂ 0.001 Mild vs severe, P ˂ 0.001 Moderate vs severe, P = 0.025
Percentage of opacity (%)	0	0.16 (1.65) [0.0025–23.4]	13.1 (16.1) [0.46–64.2]	˂0.001	Mild vs moderate, P ˂ 0.001 Mild vs severe, P ˂ 0.001 Moderate vs severe, P = 0.029
Volume of high opacity (mL)	0	0.7 (8.18) [0–174]	86 (152.5) [1.5–546]	˂0.001	Mild vs moderate, P ˂ 0.001 Mild vs severe, P ˂ 0.001 Moderate vs severe, P = 0.022
Percentage of high opacity (%)	0	0.02 (0.14) [0–7.2]	1.73 (4.34) [0.02–12.8]	˂0.001	Mild vs moderate, P ˂ 0.001 Mild vs severe, P ˂ 0.001 Moderate vs severe, P = 0.026
Mean lung density (HU)	−806 (61) [−847 to −767]	−822 (72) [−863 to −620]	−749 (136) [−818 to −542]	0.013	Mild vs moderate, P = 1.00 Mild vs severe, P = 0.026 Moderate vs severe, P = 0.017

Categorical variables are expressed as n (%), continuous variables of normal distribution are expressed as mean ± SD, continuous variables of skewed distribution are shown as median (IQR and [range]).

F, female; M, male.