Table 3. Details of nanoparticles approved by FDA with their use in treatment of different disease.
S. No. | Nanoparticles type/drug | Application |
---|---|---|
1. | Iron dextran colloid | Iron deficient anemia (Anselmo & Mitragotri, 2019) |
2. | Liposomal verteporfin | Mascular degeneration (Anselmo & Mitragotri, 2019) |
3. | Liposomal amphotericin B | Treatment and prevention of invasive fungal infection (Anselmo & Mitragotri, 2019) |
4. | Liposomal propofol | General anesthesia in open heart surgery or spinal surgery, morbidly obese patient (Anselmo & Mitragotri, 2019) |
5. | Perflutren lipid microspheres | Ultrasound contrast agent (Anselmo & Mitragotri, 2019) |
6. | Iron carboxymaltose colloid | Iron deficient anemia (Anselmo & Mitragotri, 2019) |
7. | Iron gluconate colloid | Iron deficient anemia (Anselmo & Mitragotri, 2019) |
8. | Iron sucrose colloid | Iron deficient anemia following autologous stem cell transplantation (Anselmo & Mitragotri, 2019) |
9. | Iron polyglucose carboxymethylether colloid |
Iron deficient anemia following chronic kidney disease (Anselmo & Mitragotri, 2019) |
10. | Liposomal doxorubicin | Solid malignancies, pancreatic, breast, ovarian, leukemia, prostate, liver and metastatic cancer, Kaposi’s sarcoma myeloma (Anselmo & Mitragotri, 2019) |
11. | Liposomal daunorubicin | Various leukemias, Kaposi’s sarcoma (Anselmo & Mitragotri, 2019; Obeid et al., 2018) |
12. | Albumin-particle bound paclitaxel | Solid malignancies, lymphomas, breast, bladder, lung, neck and head, pancreatic, ovarian, prostate, liver and melanoma (Anselmo & Mitragotri, 2019) |
13. | Liposomal vincristin | Brain, lymphomas, melanoma and leukemia (Anselmo & Mitragotri, 2019), (Obeid et al., 2018) |
14. | Liposomal irinotecan | Solid malignancies, pancreatic, breast, brain or sarcomas cancer (Anselmo & Mitragotri, 2019) |
11. | Cytarabine: daunorubicin liposomal formulation | Different leukemias (Anselmo & Mitragotri, 2019) |
12. | RNAi lipid protein | Transthyretin mediated amyloidosis (Anselmo & Mitragotri, 2019) |
13. | Albumin bound Paclitaxel | Metastatic breast cancer, lung cancer (Obeid et al., 2018; Desai et al., 2006) |
14. | Liposomal cytarabine | Malignant lymphomatous meningitis (Obeid et al., 2018; Desai et al., 2006) |
15. | Paclitaxel polymeric micelle | Cell lung and breast cancer (Obeid et al., 2018; Desai et al., 2006) |