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. Author manuscript; available in PMC: 2021 Nov 22.
Published in final edited form as: Shock. 2021 May 1;55(5):676–685. doi: 10.1097/SHK.0000000000001641

Fig. 6. Mortality responses.

Fig. 6.

A, Effects of sex on the dose response to cecal slurry in wild-type C57/Bl6 mice. Above each bar are the number of animals tested at each dose. P values obtained from multivariate nominal logistic analysis. B, Effects of skmIL-6 knockdown on survival to cecal slurry. Females received higher doses. No significant effects of skmIL-6KD were observed in either sex but striking differences in mortality were observed between sex. n = 10 animals in each group (total n = 40). SkmIL-6KD indicates skeletal muscle interleukin-6 knockdown.