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. 2020 Nov 13;63(12):4046–4061. doi: 10.1044/2020_JSLHR-20-00102

Table 5.

Highest multipoint LOD scores within chromosome 15q24.3-q25 in Family 315 branch analysis.

Analysis Branches included Multipoint LOD score
Individual branches Branch 1 1.33
Branch 2 −7.5
Branch 3 0.73
One branch removed; other relationships intact Branch 1 and 2 0.29
Branches 1 and 3 2.65
Branches 2 and 3 −7.12

Note. The parameters were set for recessive inheritance, omnibus language affected, full penetrance, and a disease frequency of 0.001.