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. 2021 Nov 22;160:150–174. doi: 10.1016/j.ejca.2021.10.027

Fig. 3.

Fig. 3

Most used HER2-derived peptides for the development of therapeutic peptide-based cancer vaccines. Abbreviations: EGFR; epidermal growth factor receptor; HER2, human epidermal growth factor receptor 2; HER3, human epidermal growth factor receptor 3; HER4, human epidermal growth factor receptor 4; P, phosphate; RAF, rapidly accelerated fibrosarcoma; MEK, mitogen-activated protein kinase; ERK, extracellular signal–regulated kinases; PI3K, phosphoinositide 3 kinase; MHC, major histocompatibility complex; HLA, human leukocyte antigen; aa, amino acids; ECD, extracellular domain; TMD, transmembrane domain; ICD, intracellular domain. Created with biorender.com.