Table 2. Distribution of mucopolysaccharidosis (MPS) subtypes and corresponding enzyme activity ( n  = 40) .

Type of MPS	No. of patients	Range of enzyme activity (nmol/h/mg protein)	Laboratory reference range (nmol/h/mg protein)
I IH/IHS/IS	4 (10) 2/1/1	α-L-iduronidase 1–14	20–108
II	9 (22.5)	Iduronate-2-sulfatase
	6	0–2.3	15–57
	1	0	494–1113
	1	0.05	17–46
	1	4.5	167–475
III A	7 (17.5) 2	Heparan–N-sulfatase 0.17–0.6	1.3–6.8
B	4	α-N-acetylglucosaminidase 0–1.2	6–20.5
C	1	Acetyl CoA: glucosaminide acetyltransferase 0.5	11.1–48
IVA	16 (40)	N-acetylgalactoseamine-6-sulphate sulphatase
	7	0–2.9	23–283
	1	12	24–205
	2	0–7	23–152
	4	2.3–8.6	40–70
	2	0–2.1	3.9–21
VI	4 (10)	N-acetyl galactosamine-4-sulfatase
	1	12.6	115–226
	2	6.6–6.8	8.4–45.2
	1	0.12	0.6–8.5

Abbreviations: IH, Hurler; IHS, Hurler-Scheie; IS, Scheie.

Note: Figures in parentheses represent percentage.