Fig 19. Reactivation of exhausted antitumor cells: Late administration of the treatment.

Simulation performed on the system (28a)–(28g), with (29)–(31). Evolution of the tumor mass μ₁ (plain, left axis), and of ${\overline{\mu }}_c$ (dashed, right axis) for several values of the treatment dose q. The dash-dotted line represents the time at which the treatment starts.