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. 2021 Nov 23;19:309. doi: 10.1186/s12916-021-02184-1

Table 1.

Characteristics of participants in the summer school longitudinal study. All individuals with at least one saliva sample of sufficient volume available are included

Initial visit Final visit Single visit
(N=1568) (N=1568) (N=339)
Age continuous mediana 8.0 (5.0-14.0) 7.0 (5.0-10.0)
Age stratifiedb
 Children 1181 (75.3%) 316 (93.2%)
 Adults 387 (24.7%) 23 (6.8%)
Sex
 Male 756 (48.2%) 184 (54.3%)
 Female 812 (51.8%) 155 (45.7%)
Dates collectionc
 1st week 465 (29.7%) 0 (0.0%) 59 (17.4%)
 2nd week 873 (55.7%) 46 (2.9%) 175 (51.3%)
 3rd week 216 (13.8%) 385 (24.6%) 73 (21.5%)
 4th week 14 (0.9%) 603 (38.5%) 25 (7.4%)
 5th week 0 (0.0%) 535 (34.1%) 8 (2.4%)
SARS-CoV-2 RT-PCRd
 Positive 2 (0.1%) 7 (0.4%) 2 (0.6%)
 Negative 1552 (99.2%) 1557 (99.5%) 335 (98.8%)
 Indeterminate 1 (0.1%) 1 (0.1%) 0 (0.0%)
 Not valid 9 (0.6%) 0 (0.0%) 2 (0.6%)
Symptoms
 Yes 71 (4.5%) 76 (4.8%) 16 (4.7%)
  Children 62 (5.2%) 65 (5.5%) 16 (5.1%)
  Adults 9 (2.3%) 11 (2.8%) 0 (0.0%)
 No 1492 (95.2%) 1492 (95.2%) 323 (95.3%)
  Children 1119 (94.8%) 1116 (94.5%) 300 (94.9%)
  Adults 378 (97.7%) 376 (97.2%) 23 (100%)

aMissing age of 9 adults. IQR in parenthesis

bAdult: Age 15 years or older

cAverage (median) time in days between initial and final visit was 14 (SD 6.69, IQR 7.0–21.0); 15.69 (SD 6.44, IQR 10–21) if only those with ≥ 6 days between visits are included

dIn the saliva antibody study cohort, there were 7 children and 3 adults who tested RT-PCR positive. Among them, one child and one adult were single visits. There was one adult who was positive at the first visit and negative at the last visit, and one child who was positive at both visits; therefore there were 11 positive samples. Among the paired samples, there were 8 with a positive RT-PCR at any timepoint (6 children, 2 adults). In the main infection cohort study [25], 12 participants (9 children among them) were positive by RT-PCR at least in one visit, and from 11 of them there was a saliva sample available for serology. 3446 samples were RT-PCR negative, 2 indeterminate, 11 invalid, and 7 non-available. Only 5 adults have had COVID-19 before the study