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. 2021 Nov 23;42:101350. doi: 10.1016/j.nantod.2021.101350

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Fig. 2 — Spike glycoprotein characteristics. A: Schematic comparison of the multidomain spike glycoprotein structure of SARS-CoV-1 and SARS-CoV-2. B: Schematic representation of glycosylated site differences between SARS-CoV-1-S and SARS-CoV-2-S. C: β-sheets, α-helices and disulfide bond connections in SARS-CoV-2-S RBD. D: Closed and opened states of SARS-CoV-2-S ([17]; Reproducible under Creative Commons Attribution license CC0 1.0) Signal peptide (SP), N-terminal domain (NTD), receptor-binding domain (RBD), receptor-binding motif (RBM), protease cleavage sites (S₁/S₂, S’₁), fusion peptide (FP), heptad repeat 1&2 (HR1&2), connecting domain (CD), transmembrane domain (TM) and C-terminal domain (CT).