Skip to main content
. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Am J Ophthalmol. 2021 May 26;231:58–69. doi: 10.1016/j.ajo.2021.05.012

Table 3.

Measurement Floors, Dynamic Ranges to Floors, and Steps Within the Dynamic Ranges for OCT and OCTA Metrics.

Measurement Floor Mean MD (dB) at Measurement Floor Absolute Dynamic Range Relative Dynamic Range (%) Steps to the Measurement Floor CRw
OCT Metrics
RNFL, µm 60.1 −17.8 ± 0.927 28.1 31.8 7.20 3.90b
GCIPL, µm 54.0a −23.6 ± 1.14 23.5 30.4 7.33 3.21c
Peripapillary OCTA Metrics
Custom
pVAD 0.211 −17.6 ± 1.06 0.139 39.8 2.14 0.065d
Commercial
pPDZ 0.322a −26.6 ± 1.53 0.102 24.1 4.25 0.024d
Macular
OCTA Metrics
Custom
mVAD 0.322a −21.8 ± 1.03 0.151 31.9 3.87 0.039d
mVSD 0.118a −22.0 ± 1.03 0.069 36.7 3.81 0.018d
Commercial
mPDZ 0.358a −24.9 ± 1.03 0.068 15.9 1.26 0.054d
mVDZ 14.8a −24.2 ± 1.03 2.94 16.5 1.37 2.14d
a

Measurement floors were estimated for these metrics using an arbitrary change-point MD of −20 dB per protocol delineated in text. Mean MD across measurement floors are reported with standard errors.

b

Derived from Mwanza et al. (2010)30.

c

Derived from pooled test-retest standard deviation data from Mwanza et al. (2011)31.

d

These CRw values were derived from repeatability data sets comprising non-glaucoma subjects at the USC Roski Eye Institute15.

MD = mean deviation, CRw = coefficient of repeatability, OCT = optical coherence tomography, RNFL = retinal nerve fiber layer, µm = micrometers, GCIPL = ganglion cell-inner plexiform layer, OCTA = optical coherence tomography angiography, pVAD = peripapillary vessel area density, pPDZ = peripapillary perfusion density, mVAD = macular vessel area density, mVSD = macular vessel skeleton density, mPDZ = macular perfusion density, mVDZ = macular vessel density.