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. Author manuscript; available in PMC: 2022 Dec 15.
Published in final edited form as: Eur J Med Chem. 2021 Sep 20;226:113849. doi: 10.1016/j.ejmech.2021.113849

Figure 3: Structure of pVHL - PROTAC-8 - CDK2 ternary complex.

Figure 3:

A) Ribbon representation of the energy-minimized structure of the pVHL - PROTAC-8 – CDK2 ternary complex. pVHL (grey) connected through PROTAC-8 to CDK2 (orange); B) Definition of α1, α2, α3, and α4 dihedral angles used for determination of the relative movement of the two proteins in the ternary complex