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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Kidney Int. 2021 Oct 9;100(6):1250–1267. doi: 10.1016/j.kint.2021.08.031

Table 1.

Histological scoring of kidney injury in DMSO and AAI-treated Klf15fl/fl and Klf15PTKO mice

Fibrosis Inflammation Tubular injury
Klf15fl/fl + DMSO 0.0 0.0 0.0
Klf15PTKO + DMSO 0.0 0.0 0.0
Klf15fl/fl + AAI 0.50±0.24 1.3±0.23$$ 1.8±0.28$$$
Klf15PTKO + AAI 1.0±0.0$ 2.4±0.24$$$,** 2.8±0.20$$$,*

Fibrosis, inflammation and tubular injury score: 0 (none), 1 (<10%), 2 (10–25%), 3 (25–50%) n= 4–6 mice per group

All data are expressed as mean ± SEM; $p<0.05, $$p<0.01, $$$p<0.001 versus same genotype with DMSO; *p<0.05, **p<0.01 versus AAI-treated Klf15fl/fl mice, one-way ANOVA with Sidak’s correction for multiple testing.