Table 1.
Fibrosis | Inflammation | Tubular injury | |
---|---|---|---|
Klf15fl/fl + DMSO | 0.0 | 0.0 | 0.0 |
Klf15PTKO + DMSO | 0.0 | 0.0 | 0.0 |
Klf15fl/fl + AAI | 0.50±0.24 | 1.3±0.23$$ | 1.8±0.28$$$ |
Klf15PTKO + AAI | 1.0±0.0$ | 2.4±0.24$$$,** | 2.8±0.20$$$,* |
Fibrosis, inflammation and tubular injury score: 0 (none), 1 (<10%), 2 (10–25%), 3 (25–50%) n= 4–6 mice per group
All data are expressed as mean ± SEM; $p<0.05, $$p<0.01, $$$p<0.001 versus same genotype with DMSO; *p<0.05, **p<0.01 versus AAI-treated Klf15fl/fl mice, one-way ANOVA with Sidak’s correction for multiple testing.