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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Pharmacotherapy. 2021 Oct 26;41(11):907–914. doi: 10.1002/phar.2628

Table 3.

Logistic regression of individual drugs’ association with newborn outcomes

Unadjusted ORs Adjusted ORs
Drug Any Adaptation
Syndrome
NICU Admission Any Adaptation
Syndrome
NICU Admission
Bupropion Reference Reference Reference Reference
Citalopram 0.67 (0.30-1.52) 0.87 (0.55-1.37) 1.81 (1.00-3.27)* 1.41 (0.98-2.03)
Desvenlafaxine 1.37 (0.64-2.93) 1.13 (0.72-1.77) 1.13 (0.13-9.54) 0.98 (0.26-3.74)
Duloxetine 0.91 (0.11-7.70) 0.69 (0.19-2.58) 3.04 (1.54-5.98)* 2.04 (1.29-3.23)*
Escitalopram 2.43 (1.07-5.23)* 1.96 (1.17-3.31)* 2.26 (1.30-3.95)* 1.68 (1.21-2.33)*
Fluoxetine 1.32 (0.63-2.74) 1.26 (0.82-1.94) 1.30 (0.72-2.34) 1.34 (0.96-1.87)
Paroxetine 0.85 (0.40-1.82) 1.17 (0.76-1.80) 2.60 (1.01-6.71)* 1.64 (0.83-3.26)
Sertraline 1.99 (0.70-5.65) 1.23 (0.61-2.49) 0.96 (0.57-1.63) 1.08 (0.81-1.45)
Venlafaxine 0.65 (0.32-1.33) 0.91 (0.60-1.37) 1.33 (0.58-3.06) 1.17 (0.70-1.94)

Adjusted logistic regression controlled for maternal age, race, insurance status, and estimated gestational age at birth.

Results reported as odd ratio (OR) (95% confidence interval).

*

Confidence interval does not cross 1.0, indicating a statistically significant result

NICU = neonatal intensive care unit