FIG. 3.

Histological analysis of livers from 42-day-old wild-type and null mice. Liver tissue from C57BL/6-129/SvEv hybrid mice was formalin fixed and stained with hematoxylin and eosin. The liver histology of the homozygous mutant mice compared to that of wild-type mice showed the expected liver lobular organization of the hepatic parenchyma. All sections were photographed at a magnification of ×100. (A) Wild-type mouse (WT); (B) actβC^m1/actβC^m1 mouse (actβC^−/−); (C) actβE^m1/actβE^m1 mouse (actβE^−/−); (D) actβC^m1-actβE^m1 (actβC-βE^−/−) homozygous mutant mouse. CV, central vein; PT, portal triad.