TABLE 1.
Genotype distribution from crosses of various mutant mice
| Mutant cell line | Data for mouse group
|
|||||
|---|---|---|---|---|---|---|
| +/− × +/−
|
−/− × −/−; avg litter size (total progeny/ litter no.)b | |||||
| No. with genotype (%)
|
Avg litter size (total progeny/litter no.)b | Male/female ratio (no. male/female) | ||||
| Wild type | Heterozygous | Homozygous | ||||
| βC45-F1a | 92 (26.5) | 159 (46.0) | 95 (27.5) | 9.18 (349/38) | 1.06 (181/171) | 8.03 (233/29) |
| βE82-A3 | 81 (27.1) | 152 (50.8) | 66 (22.1) | 8.82 (300/34) | 1.20 (163/136) | 8.65 (173/20) |
| βE82-C12 | 58 (25.9) | 117 (52.2) | 49 (21.9) | 8.30 (224/27) | 0.95 (109/114) | 7.20 (123/17) |
| βCβE82-A9 | 72 (29.9) | 110 (45.6) | 59 (24.5) | 8.03 (241/30) | 0.85 (111/130) | —c |
| βCβE82-G12 | 64 (25.8) | 128 (51.6) | 56 (22.6) | 8.55 (248/29) | 0.89 (116/130) | 7.40 (140/19) |
a
Data for βC46-H3 are not shown due to small sample size and few F2 progeny.
b
Total litter size was used, including nongenotyped mice.
c
—, not determined.