Fig. 2.

The effects of Aprepitant administration on hematoma volume, hemoglobin levels, brain edema, and neurobehavior tests at 24-h post-ICH. A Representative photograph of brain sections, B–C quantitative analyses of hematoma volume and hemoglobin level, D brain water content, E modified Garcia test, F corner turn test, and G forelimb placement test at 24 h after ICH. Data was represented as mean ± SD. *p < 0.05 vs sham; @p < 0.05 vs ICH + vehicle; #p < 0.05 vs ICH + Aprepitant 40 mg/kg; &p < 0.05 vs Aprepitant 360 mg/kg. One-way ANOVA, Tukey test, n = 6/group. RB right basal ganglia, RC right cortex, LB left basal ganglia, LC left cortex, CB cerebellum