Table 2.

Number of immune cells in the CNS

Organ	Day post-immunization	Treatment	N CD45 (× 105)	N CD4 (× 105)	N CD8a (× 105)	N CD11b (× 105)	N CD19 (× 105)
Spinal cord	Day 14	IgG1	1.79 ± 0.44	0.73 ± 0.19	0.16 ± 0.04	0.11 ± 0.03	0.38 ± 0.12
		Anti-BMP-2/4 Ab	1.41 ± 0.43	0.64 ± 0.17	0.11 ± 0.04	0.07 ± 0.02	0.26 ± 0.12
	Day 41	IgG1	2.54 ± 1.14	1.35 ± 0.70	0.36 ± 0.15	0.07 ± 0.02	0.14 ± 0.07
		Anti-BMP-2/4 Ab	2.65 ± 0.67	1.17 ± 0.28	0.41 ± 0.15	0.06 ± 0.01	0.26 ± 0.09
Brain	Day 14	IgG1	2.01 ± 0.45	0.67 ± 0.20	0.17 ± 0.05	0.04 ± 0.01	0.80 ± 0.11
		Anti-BMP-2/4 Ab	2.65 ± 0.25	1.25 ± 0.14	0.23 ± 0.02	0.06 ± 0.01	0.63 ± 0.14
	Day 41	IgG1	1.58 ± 0.91	0.62 ± 0.42	0.18 ± 0.11	0.04 ± 0.01	0.32 ± 0.15
		Anti-BMP-2/4 Ab	1.10 ± 0.49	0.42 ± 0.18	0.17 ± 0.08	0.02 ± 0.01	0.24 ± 0.11