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. 2021 Jul 7;18(3):1637–1649. doi: 10.1007/s13311-021-01067-w

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Fig. 1 — Press and pulse model for neurometabolic degenerative disease. Hypothetical intervention begins at week 4 in the home (orange arrow, “NK diet starts”) with ketone meter, BP cuff and weekly lab testing, showing improved metabolic syndrome parameters. Instructions to fast (time-restricted feeding or intermittent) and/or exercise produces episodically elevated ketosis (red arrows)