Table 2.

Clinical outcomes

Relapses	All patients (n = 17)	Responder (n = 10)	Non-responder (n = 7)
Patients with confirmed relapse from visit 2 to treatment termination (n (%))	4 (23.5)	0 (0.0)	4 (57.1)
1 relapse (n(%))	2 (11.8)	0 (0.0)	2 (28.6)
2 relapses (n(%))	2 (11.8)	0 (0.0)	2 (28.6)
Annualized relapse rate (ARR)	0.47	0	1.14
EDSS
Patients with EDSS increase from visit 2 to treatment termination (n (%))	6 (35.3)	0 (0.0)	6 (85.7)
Change from visit 2 to visit 4 (median (range))	0.0 (− 1.5–1.5)	− 0.5 (− 1.5–0)	0.5 (0.0–1.5)
Infections
Patients with infections from visit 2 to treatment termination (n (%))	9 (53.0)	4 (40.0)	5 (71.4)
Number of infections from visit 2 to treatment termination	14	7	7