Table 1.
Clinicopathological data of patients’ cohort
| Variable | Patients’ cohort (n = 46) median (range) |
|---|---|
| Age | 9 (2–15) years |
| Number of cases (%) | |
| Gender | |
| Male | 28 (60.9) |
| Female | 18 (39.1) |
| Grade | |
| I | 22 (47.8) |
| II | 7 (15.2) |
| III | 2 (4.34) |
| IV | 15 (32.6) |
| Tumor location | |
| Cerebellum | 37 (80.4) |
| Brain stem | 5 (10.9) |
| Temporal lobe | 1 (2.2) |
| Occipital lobe | 1 (2.2) |
| Frontal lobe | 1 (2.2) |
| 3rd ventricle | 1 (2.2) |
| P53 expression (%) | 36 (78.26) |
| H3K27M expression | 11 (24) |
| BRAFV600E mutation | 1 (2.2) |
| H3G34V mutation | 2 (4.3) |
| IDH1 R132H expression | 0 |
| Surgery (total) | 46 (100) |
| Partial resection | 24 (52.2) |
| Complete resection | 22 (47.8) |
| Radiotherapy | |
| Yes | 15 (32.6) |
| No | 31 (67.4) |
| Chemotherapy (TMZ) | |
| Yes | 16 (34.7) |
| No | 30 (65.2) |