Table 3.

Distribution (H-score) of SETDB1, SUV39H1, EZH2, MLL2, and SETD2 in normal brain tissues and astrocytomas (grades I–IV)

	SETDB1	SUV39H1	EZH2	MLL2	SETD2
	Mean (range)/no. of positive cases/total
NB	15 (25–50)/ 2/5	0	0	32 (10–70)/ 4/5	0
Total	128 (10–285)/ 43/46	96 (2–300)/ 31/46	1.4(0.5–12.5)/ 10/46	66 (3–270)/ 28/46	173 (10–300)/ 46/46
Grade I	116 (20–270)/ 20/22	112 (25–300)/ 16/22	1.9 (0.5–12.5)/ 6/22	25 (4–160)/ 10/22	183 (10–300)/ 22/22
Grade II	77 (10–255)/ 7/7	101 (10–270)/ 5/7	1.4 (10)/ 1/7	112 (3–240)/ 6/7	149 (70–297)/ 7/7
Grade III	170 (70–270)/ 2/2	15 (30)/ 1/2	6 (2–10)/ 2/2	60 (120)/ 1/2	110 (30–190)/ 2/2
Grade IV	165 (30–285)/ 14/15	65 (2–270)/ 9/15	0.2 (3)/ 1/15	105 (15–270)/ 11/15	177 (40–300)/ 15/15