Table 5.
Univariate analysis of variables with progression.
| Variables | Reference | HR | LCI (95%CIHR) | UCI (95%CIHR) | p-value | |
|---|---|---|---|---|---|---|
| OncotypeDx® | RS low | 0 | ||||
| RS intermediate | 1 | 0.973 | 0.088 | 10.735 | 0.982 | |
| RS high | 2 | 4.871 | 0.387 | 61.359 | 0.221 | |
| Mammaprint® | Low | 0 | ||||
| High | 1 | 0.497 | 0.095 | 2.612 | 0.409 | |
| Age(years) | ≤50 | 1 | 1.608 | 0.424 | 6.101 | 0.485 |
| >50 | 0 | |||||
| Grade | G1 | 0 | ||||
| G2 | 1 | 0.53 | 0.151 | 0.41 | 0.321 | |
| G3 | 2 | 0.986 | ||||
| Lymphovascular invasion | Positive | 0 | ||||
| Negative | 1 | 1.291 | 0.155 | 10.742 | 0.813 | |
| Lymph nodes | N0 | 1 | 0.838 | 0.178 | 3.953 | 0.823 |
| N1/N1mi | 1 | 1.227 | 0.26 | 5.787 | 0.796 | |
| Subtype luminal | A | 0 | ||||
| B | 1 | 0.191 | 0.041 | 0.902 | 0.037 | |
| Margins | R1 | 1 | 4.364 | 1.311 | 14.528 | 0.016 |
| R0 | 0 | 0 | 0 | 0 | ||
| Ki 67 | ≤20% | 0 | ||||
| >20% | 1 | 0.412 | 0.087 | 1.944 | 0.262 | |
| Type of treatment | Surgery + RT | 1 | 0.949 | 0.201 | 4.473 | 0.947 |
| Surgery | 0 | |||||
| Systemic treatment | HT | 0 | ||||
| QT + HT | 1 | 1.251 | 0.366 | 4.273 | 0.721 |
Abbreviations: Surgery (Lumpectomy; Mastectomy), QT (Chemotherapy), HT (hormone therapy).