Fig. 6.

Supra- and sub-threshold patterns of pyramidal neuron and interneurons of the superficial neocortical layers (layers II/III). A, Examples of superficial layer pyramidal neurons (PY) and interneurons (IN) from wildtypes (S-WTs), heterozygotes (S-HTs), and knockouts (KOs). B, Sag voltage for the response to current injection of -200pA (average ± SEM for all animals tested). Arrow on time series indicates definition used for sag voltage. Bar plot shows summary of average sag voltage (* p = 0.04761; ** p = 0.00322 unpaired t-test). C, Post-inhibitory rebound depolarization (R.D.) for the -200pA current injection. Left curve shows pre-stimulus baseline and middle curve shows post-stimulus R.D.. Arrow on time series indicates definition used for R.D.. Bar plot shows summary of average R.D. (S-WT vrs S-HT p = 0.24947; * p = 0.00393; unpaired t-test). For n's, see Table 1.