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. 2021 Nov 16;9(12):e1679–e1687. doi: 10.1016/S2214-109X(21)00367-3

Table 3.

Total and per-person estimates of the burden of disease caused by incident tuberculosis in 2019

Total tuberculosis cases (thousands) Absolute DALYs (millions)
DALYs per incident tuberculosis case
Tuberculosis disease Post-tuberculosis Total Tuberculosis disease Post-tuberculosis Total
All 9954 (8952–11 003) 63·79 (53·87–75·16) 57·76 (38·37–82·97) 121·55 (98·29–151·19) 6·41 (5·69–7·20) 5·80 (3·83–8·34) 12·21 (10·02–14·85)
Age group
1–4 years 1185 (1065–1309) 10·75 (8·97–13·02) 10·26 (6·51–15·03) 21·00 (16·61–26·56) 9·07 (7·92–10·80) 8·66 (5·52–12·92) 17·73 (14·16–21·99)
15–34 years 3307 (2974–3655) 14·43 (12·16–17·06) 24·32 (16·14–35·07) 38·75 (29·76–50·70) 4·36 (3·85–4·97) 7·36 (4·82–10·71) 11·72 (9·12–15·03)
35–54 years 3039 (2733–3359) 22·06 (18·72–25·77) 16·32 (10·85–23·19) 38·37 (31·55–46·87) 7·26 (6·47–8·18) 5·37 (3·59–7·65) 12·63 (10·61–15·02)
55–74 years 1998 (1797–2208) 14·41 (12·26–16·76) 6·29 (4·27–9·00) 20·69 (17·61–24·29) 7·21 (6·41–8·01) 3·15 (2·17–4·45) 10·36 (9·09–11·79)
≥75 years 426 (383–471) 2·15 (1·83–2·51) 0·58 (0·40–0·83) 2·73 (2·33–3·19) 5·05 (4·47–5·65) 1·36 (0·95–1·92) 6·41 (5·77–7·17)
Sex
Male 6158 (5538–6807) 39·75 (33·58–46·81) 35·61 (23·69–51·05) 75·36 (61·12–93·50) 6·45 (5·73–7·24) 5·78 (3·85–8·26) 12·24 (10·10–14·82)
Female 3796 (3414–4196) 24·04 (20·29–28·35) 22·15 (14·63–32·05) 46·19 (37·13–57·77) 6·33 (5·62–7·13) 5·84 (3·81–8·50) 12·17 (9·93–14·84)
Tuberculosis incidence level (cases per 100 000 population)
<10 51 (46–56) 0·13 (0·11–0·15) 0·08 (0·03–0·18) 0·21 (0·15–0·31) 2·48 (2·15–2·87) 1·60 (0·50–3·68) 4·08 (2·93–6·30)
10–49 331 (298–366) 1·05 (0·89–1·25) 1·02 (0·58–1·58) 2·07 (1·58–2·69) 3·19 (2·78–3·62) 3·08 (1·82–4·84) 6·27 (4·92–8·02)
50–199 4726 (4250–5224) 29·43 (24·90–34·33) 23·70 (16·26–34·37) 53·13 (43·57–64·51) 6·23 (5·53–6·95) 5·02 (3·47–7·10) 11·24 (9·53–13·53)
≥200 4846 (4359–5357) 33·19 (28·02–39·07) 32·96 (20·25–49·02) 66·14 (52·32–83·97) 6·85 (6·05–7·81) 6·80 (4·09–10·14) 13·65 (10·79–17·05)
HIV status
HIV positive 999 (899–1104) 11·84 (10·12–13·84) 5·81 (3·78–8·44) 17·65 (14·84–21·04) 11·85 (10·59–13·39) 5·82 (3·79–8·51) 17·67 (15·27–20·45)
HIV negative 8955 (8053–9898) 51·95 (43·86–61·16) 51·95 (34·55–74·36) 103·90 (83·26–130·27) 5·80 (5·13–6·54) 5·80 (3·83–8·36) 11·60 (9·44–14·24)
Tuberculosis treatment
Treated 7224 (6230–8270) 17·43 (9·75–28·92) 43·84 (28·17–64·45) 61·27 (40·87–86·32) 2·39 (1·48–3·59) 6·07 (4·09–8·76) 8·46 (6·10–11·35)
Untreated 2730 (1999–3530) 46·36 (33·70–60·53) 13·92 (8·04–22·31) 60·28 (43·59–79·15) 16·99 (15·24–18·81) 5·10 (3·27–7·55) 22·09 (19·51–24·84)

Values in parentheses represent 95% uncertainty intervals. DALYs=disability-adjusted life-years.