Table.
Baseline demographic characteristics and HIV risk behaviour of individuals initiating PrEP and predictors of having at least one refill visit in the first 3 months
| All participants initiating PrEP (n=4898) | Participants with at least one visit within 3 months of PrEP start (n=3028) | OR (95%CI) | ||
|---|---|---|---|---|
| Demographics | ||||
| Gender | ||||
| Men | 2257 (46%) | 1355/2257 (60%) | 1 (ref) | |
| Women | 2640 (54%) | 1672/2640 (63%) | 1·15 (1·03–1·29) | |
| Age, years | ||||
| 18–24 | 969 (20%) | 526/969 (54%) | 1 (ref) | |
| 25–34 | 2118 (43%) | 1304/2118 (62%) | 1·35 (1·16–1·57) | |
| ≥35 | 1811 (37%) | 1198/1811 (66%) | 1·65 (1·40–1·93) | |
| Marital status | ||||
| Single | 347 (7%) | 137/347 (39%) | 1 (ref) | |
| Married or cohabitating | 4466 (91%) | 2843/4466 (64%) | 2·67 (2·15–3·35) | |
| Widowed or separated | 85 (2%) | 48/85 (56%) | 1·99 (1·23–3·21) | |
| Reported HIV risk behaviour | ||||
| Has HIV positive partner | 4092 (84%) | 2676/4092 (65%) | 2·44 (2·09–2·84) | |
| Inconsistent or no condom use | 2817 (58%) | 1741/2817 (62%) | 1·00 (0·89–1·12) | |
| Unknown status of sex partner | 789 (16%) | 379/789 (48%) | 0·51 (0·44–0·59) | |
| Multiple partners | 565 (12%) | 267/565 (47%) | 0·51 (0·43–0·61) | |
| Recurrent sex under the influence of alcohol | 111 (2%) | 54/111 (49%) | 0·58 (0·40–0·84) | |
| Engaging in transactional sex | 67 (1%) | 26/67 (39%) | 0·38 (0·24–0·63) | |
| Recurrent PEP use | 55 (1%) | 31/55 (56%) | 0·80 (0·47–1·36) | |
| Recent sexually transmitted infection | 44 (1%) | 27/44 (61%) | 0·98 (0·53–1·80) | |
| Ongoing intimate-partner or gender-based violence | 35 (1%) | 17/35 (49%) | 0·58 (0·30–1·12) | |
| Injection drug use | 5 (<1%) | 5/5 (100%) | .. | |
| Not circumcised (men only)* | 385/1965 (20%) | 237/385 (62%) | 0·99 (0·82–1·20) | |
| Characteristics of HIV serodiscordant couples (n=4092) | ||||
| Number of children with partner* | ||||
| 0 | 888/2502 (35%) | 618/888 (70%) | 1 (ref) | |
| 1–2 | 957/2502 (38%) | 653/957 (68%) | 0·94 (0·77–1·14) | |
| 3 or more | 657/2502 (26%) | 469/657 (71%) | 1·09 (0·87–1·36) | |
| Time known to be discordant | ||||
| <1 year | 1093/2468 (44%) | 743/1093 (68%) | 1 (ref) | |
| 1–3 years | 613/2468 (25%) | 432/613 (70%) | 1·12 (0·91–1·39) | |
| >3 years | 760/2468 (31%) | 538/760 (71%) | 1·14 (0·93–1·40) | |
| HIV risk score† | ||||
| 0–2 | 1247/4092 (31%) | 785/1247 (63%) | 1 (ref) | |
| ≥3 | 2845/4092 (70%) | 1891/2845 (67%) | 1·17 (1·02–1·34) | |
| Pregnancy and fertility (n=2640 women) | ||||
| Pregnant* | 167/1486 (11%) | 114/167 (68%) | 1·26 (0·90–1·78) | |
| Breastfeeding* | 262/1687 (16%) | 163/262 (62%) | 0·89 (0·68–1·17) | |
| Using contraception* | 968/1820 (53%) | 633/968 (65%) | 0·90 (0·74–1·09) | |
| Fertility desires* | ||||
| No fertility desires | 648/1510 (43%) | 400/648 (62%) | 1 (ref) | |
| Immediate | 318/1510 (21%) | 241/318 (76%) | 1·94 (1·44–2·62) | |
| Future | 479/1510 (32%) | 309/479 (65%) | 1·13 (0·88–1·44) | |
| Don't know | 65/1510 (4%) | 40/65 (62%) | 0·99 (0·59–1·68) | |
Data are n (%) or n/N (%), unless otherwise specified. PEP=post-exposure prophylaxis. PrEP=pre-exposure prophylaxis.
There are missing data for various variables as follows: male circumcision 292 (13%), number of children with partner 1590 (39%), time known to be HIV discordant 1624 (40%), pregnancy 1154 (44%), breastfeeding 771 (31%), contraception 820 (31%), and fertility desires 1130 (43%).
HIV risk score was calculated from the following characteristics: age of the HIV uninfected partner, number of children within the partnership, circumcision status of HIV uninfected men, whether the couple was cohabiting, and having unprotected sex in the month before starting PrEP.