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. 2019 Jan 28;48(8):2626–2634. doi: 10.1039/c8dt04350g

Ruthenium(ii) complexes investigated by ESI-MS and their biological activity.

Complex 1 2 3
Notation [Ru(CYM)(p-Cl-dkt)Cl] [Ru(CYM)(pta)(p-Cl-dkt)]PF6 [Ru(CYM)(pta)Cl2] (RAPTA-C)
Formula graphic file with name c8dt04350g-u1.jpg graphic file with name c8dt04350g-u2.jpg graphic file with name c8dt04350g-u3.jpg
IC50 [μM] ovarian cell 17 8 65 ± 15 (ref. 13)
IC50 [μM] osteosarcoma 64 41
ROS production Yes No No
Cell uptake Jurkat cellsa 1.5 × 10−4 ng 1 × 10−4 ng 5 × 10−5 ng
a

Concentration of 1–3 was 10 μM. See ref. 2 for more details.