Table II.
Comparison of the immunosenescence markers between healthy controls and systemic lupus erythematosus patients
Variable | Healthy controls (n = 53) | SLE patients (n = 53) | p-value |
---|---|---|---|
CD4+CD57+ [%] | 1.0 (0.4–1.4) | 1.2 (0.6–2.8) | 0.108 |
CD4+KLRG1+ [%] | 0.3 (0.1–0.5) | 3.1 (1.3–5.5) | 0.000* |
CD8+CD57+ [%] | 2.4 ±2.0 | 11.6 ±7.1 | 0.000* |
CD8+KLRG1+ [%] | 0.3 ±0.1 | 13.7 ±7.5 | 0.000* |
IFN-γ levels [pg/ml] | 6.2 (5.3–8.9) | 193.1 (139.1–225.1) | 0.000* |
IFN-γ – interferon γ, KLRG1 – killer cell lectin like receptor G1
p < 0.05 considered significant.