Table V.
Comparison of immunosenescence markers according to disease activity status of systemic lupus erythematosus patients
Variable | Inactive SLE patients (n = 12) | Active SLE patients (n = 41) | p-value |
---|---|---|---|
CD4+CD57+ [%] | 1.2 (0.7–2.4) | 0.8 (0.6–1.9) | 0.444 |
CD4+KLRG1+ [%] | 2.1 (1.3–5.0) | 2.5 (1.2–4.6) | 0.772 |
CD8+CD57+ [%] | 7.9 ±6.9 | 12.7 ±6.9 | 0.041* |
CD8+KLRG1+ [%)] | 8.4 ±5.3 | 15.2 ±7.4 | 0.004* |
IFN-γ levels [pg/ml] | 146.7 (130.2–210.8) | 208.9 (148.3–233.8) | 0.048* |
IFN-γ – interferon γ, KLRG1 – killer cell lectin like receptor G1
p < 0.05 considered significant.