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. 2021 Jul 22;16(5):598–611. doi: 10.1016/j.ajps.2021.04.002

Fig. 4.

Fig 4

Safety of GCE and antiproliferation effect of GCE/siRNA in vitro. (A) The cytotoxicity of GCE on MCF-7 cells using MTT method. (B) Anti-proliferation effect of GCE/siRNA in MCF-7 cells. The results were presented as the mean ± SD, n = 3. (C) Effect of GCE/siRNA on apoptosis morphology of MCF-7 cells. (D) Cell cycle distribution of MCF-7 cells treated by survivin-siRNA for 48 h. (a) Distribution of MCF-7 cell cycle detected by flow cytometry in different treatment groups. (b) Statistical chart of cell cycle distribution of MCF-7 cells in different treatment groups. (E) The apoptosis of MCF-7 cells induced by siRNA for 48 h. (a) Flow cytometric plot of rate of apoptosis by annexin V and PI staining of MCF-7 cells. (b) Apoptosis rate of MCF-7 cells in different treatment groups. The cells with no treatment was considered as a control. The data were presented as the mean ± SD, n = 3.