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. 2021 Jul 22;16(5):598–611. doi: 10.1016/j.ajps.2021.04.002

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© 2021 Shenyang Pharmaceutical University. Published by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig 5 — Migration and invasion inhibition effects of GCE/siRNA on MCF-7 cells. (A) Effect of survivin-siRNA on MCF-7 cells migration by wound healing assay. (a) Photographs of MCF-7 cells in different treatment groups at 0, 24 and 48 h by wound healing assay. (b) Statistical chart of cell migration rate of MCF-7 cells in different treatment groups. (B) Migration by transwell assay. (a) Control, (b) GCE/NC, (c) GCE/siRNA, (d) Statistical chart of number of migrated MCF-7 cells in different treatment groups. (C) Effect of invasion by transwell assay. (a) Control, (b) GCE/NC, (c) GCE/siRNA, (d) Statistical chart of number of invaded MCF-7 cells in different treatment groups. The cells with no treatment were considered as a control. The data were presented as the mean ± SD, n = 3.