Evaluation of localization technique using randomly distributed PTs (n = 5 for each density). Localization results of PTs with a density of 55.62 PTs/mm2 are shown in (a) 2DCC, (b) CVX-CS, and (c) L1H-CS algorithms. Localized points by 2DCC, CVX-CS, and L1H-CS are blue, green, and red asterisks overlaid with B-mode images, while black circles show the positions of simulated PTs. The overlapped points were localized by CS algorithm, but 2DCC could not localize them as shown in the insets images of (a-c). (d) Localization efficiency, (e) error, and (f) computational time depending on PTs density from 2.65 to 174.8 PTs/mm2 describe that CVX-CS and L1H-CS algorithms can efficiently localize simulated PTs with 90% yield up to the density of 55.62 PTs/mm2, while 2DCC can localize PTs with 90% yield up to the PT density of 15.89 PTs/mm2. The Black dashed line indicates ideal match between simulated points and localized points by each algorithm. Image size is 62×62 pixels and scale bars indicate 250 μm.