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. Author manuscript; available in PMC: 2021 Nov 23.
Published in final edited form as: Cell Rep. 2021 Oct 19;37(3):109845. doi: 10.1016/j.celrep.2021.109845

Figure 5. Post-oral sensing of a HFD increases ad libitum caloric intake and body weight in the absence of oral taste sensing.

Figure 5.

(A) Design of the experiment for data in (B)–(E) in which all animals are given ad libitum access to oLFD. n = 5–6/group.

(B) Infused kcals and ad libitum kcals consumed.

(C) Average ad libitum intake during 11-kcals infusions with LFD or HFD.

(D) Body weight during infusions.

(E) Experimental design for (F) and (G) (n = 6).

(F) Infused and ad libitum caloric intake.

(G) Average intake of days 4–5 during iLFD compared with that of days 6–14 during iHFD. Data are displayed as mean ± standard deviation or as individual data points in (C). *p < 0.05, comparing iLFD diet group to iHFD using a Student’s t test except in (C) and (G) for which paired t tests were used for within-group comparisons. Unshaded bars show intake during iLFD while black bars show intake during iHFD.