Table 2.
Acoustic, lexical, and cognitive characteristics of patient groups and healthy controls
| Mean (Standard Deviation) | Healthy controls | PSPS-CBS | naPPA | p 1 |
|---|---|---|---|---|
| n | 41 | 87 | 25 | |
| Speech segment duration (s) | 2.00 (0.57) | 1.42 (0.48)*,P | 1.17 (0.50)* | <0.001 |
| Pause segment duration (s) | 0.93 (0.44) | 1.82 (1.01)* | 1.65 (1.10)* | <0.001 |
| Pause rate (ppm) | 31.61 (9.51) | 45.10 (13.43)*,P | 57.81 (19.95)* | <0.001 |
| n (f0 range) | 36 | 74 | 20 | |
| f0 range (ST) | 5.87 (1.94) | 4.97 (2.03)* | 4.30 (1.59)* | 0.010 |
| Speech rate (wpm) | 144.95 (32.12) | 89.03 (36.70)*,P | 65.15 (25.55)* | <0.001 |
| Partial words | 0.52 (0.96) | 1.33 (2.93)P | 3.67 (5.25)* | 0.013 |
| Verb production | 23.07 (3.45) | 23.19 (4.56)P | 19.99 (4.46)* | 0.013 |
| Noun production | 20.06 (4.53) | 22.20 (4.98)* | 21.40 (8.33) | 0.055 |
| Grammatical performance score2 | 0.00 (0.78) | −0.84 (1.13)* | −1.48 (1.71)* | <0.001 |
| n | 26 | 67 | 18 | |
| Boston Naming Test score | 28.12 (2.45) | 24.46 (6.19)* | 24.17 (4.69)* | 0.001 |
| n | 26 | 62 | 18 | |
| Delayed Verbal Recall score | 7.04 (1.82) | 5.55 (2.56)* | 5.67 (2.93) | 0.034 |
| n | 26 | 57 | 19 | |
| Rey-Osterrieth Complex Figure | 34.54 (2.11) | 22.21 (10.90)* | 25.58 (9.83)* | <0.001 |
| n | 4 | 50 | 15 | |
| F-letter Fluency score | 17.75 (8.10) | 6.72 (3.57)* | 5.93 (3.39)* | 0.038 |
PSPS, progressive supranuclear palsy syndrome; CBS, corticobasal syndrome; naPPA, non-fluent/agrammatic primary progressive aphasia; s, seconds; ppm, pauses per minute of speech time; ST, semitones; wpm, words per minute; f0, fundamental frequency.
1
p-values for all contrasts in main groups: HC, PSPS-CBS, and naPPA:
*
differs from HC
P
differs from naPPA.
2
Values are z-scores of averaged dependent clauses per 100 utterances and percentage of utterances that are well-formed sentences, using control mean and standard deviation.