Fig. 3.

Preinfection levels of CD4⁺ iNKT cells are associated with the peak VL. Frequency of peripheral blood iNKT (A) and CD4⁺ iNKT cells (B) for individuals enrolled in RV217 that did not become HIV infected (n = 20) or became HIV infected (n = 22). The lines and whiskers represent the median and interquartile range, respectively. Associations between peripheral blood iNKT (C), CD4⁺ iNKT (D), and CD4⁻ iNKT cells (E) preinfection frequencies and peak VL (n = 22). Associations between peripheral blood CD4⁺ CCR5⁺ iNKT cells (n = 10) (F) or conventional CD4⁺ CCR5⁺ T cells (n = 10) (G) frequency and peak VL.