Table 3.
Antifungal Treatment Received and Antifungal Susceptibility Testing Result Availability by Candida Species of Adult Candidemia Patients (N = 1801)—9 Surveillance Sites, United States, 2017–2018
|
Candida Species From First Positive Blood Culturea |
Initial Antifungal Drug Administered |
Tested for Antifungal Susceptibility |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Total (N = 1801) | % | Echinocandin (n = 1258) | % | Fluconazole (n = 543) | % | Fluconazole (n = 968) | % | Echinocandin (n = 720) | % | |
| C albicans | 695 | 38.6 | 456 | 65.6 | 239 | 34.4 | 366 | 52.7 | 241 | 34.7 |
|
| ||||||||||
| C glabrata | 530 | 29.4 | 385 | 72.6 | 145 | 27.4 | 260 | 49.1 | 226 | 42.6 |
|
| ||||||||||
| C parapsilosis | 237 | 13.2 | 161 | 67.9 | 76 | 32.1 | 133 | 56.1 | 103 | 43.5 |
|
| ||||||||||
| C tropicalis | 129 | 7.2 | 96 | 74.4 | 33 | 25.6 | 67 | 51.9 | 45 | 34.9 |
|
| ||||||||||
| C krusei b | 32 | 1.8 | 23 | 71.9 | 9 | 28.1 | 32 | 100.0 | 16 | 50.0 |
|
| ||||||||||
| C lusitaniae | 31 | 1.7 | 19 | 61.3 | 12 | 38.7 | 18 | 58.1 | 15 | 48.4 |
|
| ||||||||||
| C dubliniensis | 23 | 1.3 | 18 | 78.3 | 5 | 21.7 | 16 | 69.6 | 14 | 60.9 |
|
| ||||||||||
| Other non-albicans species | 75 | 4.2 | 61 | 81.3 | 14 | 18.7 | 42 | 56.0 | 37 | 49.3 |
|
| ||||||||||
| >1 speciesc | 49 | 2.7 | 39 | 79.6 | 10 | 20.4 | 34 | 69.4 | 23 | 46.9 |
Abbreviation: C, Candicans.
Rows are mutually exclusive.
Fluconazole susceptibility results were considered known for all of these patients because C krusei is an inherently fluconazole-resistant species.
C albicans was one of the species present for 32 of the patients whose initial blood culture grew >1 species.