Table 2.
Demographics of PD cases and controls in cohort 1 and cohort 2
| PD cases | Controls | p | ||||
| N | N | |||||
| Age, mean (SD), y | Cohort 1 | 71.0 (11.2) | 9,852 | 49.8 (17.4) | 1,206,650 | < 0.0001 |
| Cohort 2 | 71.1 (11.0) | 10,072 | 49.8 (17.4) | 1,206,437 | < 0.0001 | |
| Female, no. (%) | Cohort 1 | 3,967 (40.3%) | 9,852 | 665 524 (55.2%) | 1,206,650 | < 0.0001 |
| Cohort 2 | 3,901 (38.7%) | 10,072 | 665 325 (55.1%) | 1,206,437 | < 0.0001 | |
| Education, mean (SD), y | Cohort 1 | 16.3 (2.8) | 7,058 | 15.8 (2.7) | 1,069,986 | < 0.0001 |
| Cohort 2 | 16.3 (2.8) | 7,306 | 15.8 (2.7) | 1,070,797 | < 0.0001 | |
| Ever-smokers, no. (%) | Cohort 1 | 3,202 (37.8%) | 8,461 | 428 924 (37.6%) | 1,140,204 | 0.669 |
| Cohort 2 | 3,396 (39.3%) | 8,631 | 428 280 (37.6%) | 1,140,047 | < 0.0001 | |
| 0 alcohol measures over last 2 weeks, no. (%) | Cohort 1 | 3,133 (46.4%) | 6,745 | 374 145 (34.0%) | 1,099,968 | < 0.0001 |
| Cohort 2 | 3,235 (47.2%) | 6,847 | 374 702 (34.0%) | 1,100,536 | < 0.0001 | |
| BMI, mean (SD), kg/m2 | Cohort 1 | 26.7 (5.2) | 9,852 | 27.5 (6.0) | 1,206,650 | < 0.0001 |
| Cohort 2 | 26.7 (5.2) | 10,072 | 27.5 (6.0) | 1,206,437 | < 0.0001 | |
PD, Parkinson’s disease; SD, standard deviation; N, number of individuals in a cohort.