Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Long-term BTKi treatment normalises lymphocyte subset frequency and reduces PD-1 expression. Frequency of CD19 + B cells (A), CD3 + T cells (B) and CD4:CD8 ratio (C) in PBMC from CLL patients collected prior to treatment (baseline), after long-term treatment of ibrutinib (n = 7) or zanubrutinib (n = 8) and age-matched healthy donors (HD, n = 7). PD-1 median fluorescence intensity (MFI) on CD8 + (D) and CD4 + (E) T cells
