Table 1.
Patient | Diagnosis | Complement Mutations | Age (yr) | Sex | Eculizumab Treatment | Creatinine (mg/dL) |
LDH (U/L) |
PLT (K/cu mm) |
mHam (%) | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|
At Diagnosis | Post Ecu | At Diagnosis | Post Ecu | At Diagnosis | Post Ecu | |||||||
aHUSCFH | aHUS | CFH1 Gln950His heterozygous, del (CFHR1-CHFR3) homozygous | 53 | F | yes | 1.6 | 0.9 | 2505 | 180 | 9 | 327 | 43.2 ± 0.125 |
aHUSnone | aHUS | None detected | 27 | F | yes | 6.3 | 1.2 | 2820 | 195 | 62 | 251 | 36.1 ± 0.099 |
aHUSCFI | aHUS | CFI Ile416Leu heterozygous, Thr300Ala homozygous | 53 | F | yes | 4.8 | On iHD |
3459 | 231 | 5 | N/A | 90.3 ± 13.18 |
APS | APS | Not performed | 43 | M | no | 11.2 | N/A | 168 | N/A | 61 | N/A | 51.7 ± 9.36 |
LDH Lactate Dehydrogenase, PLT Platelet count, Ecu Eculizumab. iHD intermittent hemodialysis.