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. Author manuscript; available in PMC: 2021 Nov 23.
Published in final edited form as: Clin Immunol. 2020 Oct 24;221:108616. doi: 10.1016/j.clim.2020.108616

Table 1.

Clinical characteristics of atypical hemolytic uremic syndrome and antiphospholipid antibody syndrome patients

Patient Diagnosis Complement Mutations Age (yr) Sex Eculizumab Treatment Creatinine (mg/dL)
LDH (U/L)
PLT (K/cu mm)
mHam (%)
At Diagnosis Post Ecu At Diagnosis Post Ecu At Diagnosis Post Ecu
aHUSCFH aHUS CFH1 Gln950His heterozygous, del (CFHR1-CHFR3) homozygous 53 F yes 1.6 0.9 2505 180 9 327 43.2 ± 0.125
aHUSnone aHUS None detected 27 F yes 6.3 1.2 2820 195 62 251 36.1 ± 0.099
aHUSCFI aHUS CFI Ile416Leu heterozygous, Thr300Ala homozygous 53 F yes 4.8 On
iHD
3459 231 5 N/A 90.3 ± 13.18
APS APS Not performed 43 M no 11.2 N/A 168 N/A 61 N/A 51.7 ± 9.36

LDH Lactate Dehydrogenase, PLT Platelet count, Ecu Eculizumab. iHD intermittent hemodialysis.