Table 2.
Compliance with Therapeutic Guidelines: Antibiotics recommendations
| Summary of Therapeutic Guidelines recommendations | Compliance with version 15 guidelines (2018) | Compliance with version 16 guidelines (2019) |
|---|---|---|
| All patients should receive preoperative antibiotics for internal fixations | 97.3% (180/185) | 95.6% (196/205) |
| Antimicrobial choice | ||
| Cefazolin | 97.7% (176/180) | 99.5% (195/196) |
| Vancomycin (for patients with immediate hypersensitivity to penicillin) | 0% (0/4)a | 0% (0/1)a |
| Dose (of cefazolin) | ||
| 2 g or as appropriateb | 80.6% (145/180) | 83.2% (163/196) |
| Preoperative timing of administration | ||
| Within 60 min prior to incision (for cefazolin) or within 120 min prior to incision (for vancomycin) | Not available | Not available |
| Route | ||
| IV | 100% (180/180) | 100% (196/196) |
| Intraoperative drug administration if duration of procedure ≥ 240 min | 0% (0/2) | 100% (2/2) |
| Duration of prophylaxis | ||
| Should not exceed 24 h from time of induction (version 15) | 78.3% (141/180) | – |
| Patients should receive only a single preoperative dose (version 16) | – | 20.4% (40/196) |
aPatients received clindamycin instead of vancomycin
bAppropriate dose based on age, weight, or renal function